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DKK2 antibody

CAT: 0710-FNab02402Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02402Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity) .
Synonyms
Dickkopf-related protein 2 (Dickkopf-2, Dkk-2, hDkk-2) |DKK2
Gene ID
27123
UniProt
Q9UBU2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Dickkopf homolog 2
Target
DKK2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
32 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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