DIO1 antibody

• Background:

  Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine) . Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.

• Synonyms:

  Type I iodothyronine deiodinase|5DI|DIOI|Type 1 DI|Type-I 5'-deiodinase|DIO1|ITDI1|TXDI1

• Gene ID:

  1733

• UniProt:

  P49895

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Deiodinase, iodothyronine, type I

• Target:

  DIO1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:50-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  13 kDa, 29 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC