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DHX9 antibody

CAT: 0710-FNab02383Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02383Size:100 µg
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Background
Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alteration of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Component of the CRD-mediated complex that promotes MYC mRNA stability. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms. Positively regulates HIV-1 LTR-directed gene expression.
Synonyms
ATP-dependent RNA helicase A|DEAH box protein 9|DExH-box helicase 9|Leukophysin (LKP) |Nuclear DNA helicase II (NDH II) |RNA helicase A|DHX9|DDX9|LKP|NDH2
Gene ID
1660
UniProt
Q08211
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
DEAH (Asp-Glu-Ala-His) box polypeptide 9
Target
DHX9
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

UniProtKB · Q08211

ATP-dependent RNA helicase A

DHX9_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q08211
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DHX9
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.4.13
Processing
—
Secondary accessions
B2RNV4, Q05CI5, Q12803, Q32Q22, Q5VY62, Q6PD69, Q99556
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingHelicaseHydrolaseRNA-binding

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingManganeseMetal-bindingNucleotide-binding

Disease

Autism spectrum disorderDisease variantIntellectual disability

Biological process

Biological rhythmsDNA replicationHost-virus interactionImmunityInflammatory responseInnate immunitymRNA processingmRNA splicingmRNA transportRNA-mediated gene silencingTranscriptionTranscription regulationTranscription terminationTranslation regulationTransport

Cellular component

CytoplasmCytoskeletonNucleus

Domain

Repeat

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