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DENND3 antibody

CAT: 0710-FNab02333Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02333Size:100 µg
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Background
Guanine nucleotide exchange factor (GEF) activating RAB12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.
Synonyms
DENN domain-containing protein 3|DENND3|KIAA0870
Gene ID
22898
UniProt
A2RUS2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
DENN/MADD domain containing 3
Target
DENND3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
136 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
1059-1198aa

UniProtKB · A2RUS2

DENN domain-containing protein 3

DEND3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
A2RUS2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DENND3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B7ZM28, O94947, Q2TAM7, Q6ZMS6, Q96DK3
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Molecular function

Guanine-nucleotide releasing factor

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatWD repeat

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