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DCK antibody

CAT: 0710-FNab02265Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02265Size:100 µg
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Background
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Synonyms
Deoxycytidine kinase (dCK) |Deoxyadenosine kinase|Deoxyguanosine kinase|DCK
Gene ID
1633
UniProt
P27707
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Deoxycytidine kinase
Target
DCK
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
30 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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