DAB2IP antibody

• Background:

  Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon (IFN) or lipopolysaccharide (LPS) .

• Synonyms:

  Disabled homolog 2-interacting protein (DAB2 interaction protein, DAB2-interacting protein) |ASK-interacting protein 1 (AIP-1) |DOC-2/DAB-2 interactive protein|DAB2IP|AF9Q34|AIP1|KIAA1743

• Gene ID:

  153090

• UniProt:

  Q5VWQ8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  DAB2 interacting protein

• Target:

  DAB2IP

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB,IP

• Field of Research:

  Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:5000; IP: 1:500-1:5000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  130 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IP