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KRT8 antibody

CAT: 0710-FNab02221Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab02221Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
Synonyms
Keratin, type II cytoskeletal 8|Cytokeratin-8 (CK-8) |Keratin-8 (K8) |Type-II keratin Kb8|KRT8|CYK8
Gene ID
3856
UniProt
P05787
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Keratin 8
Target
KRT8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC
Field of Research
Stem Cells, Immunology, Developmental biology, Cancer
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
53 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC

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