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CYP11B2 antibody

CAT: 0710-FNab02144Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02144Size:100 µg
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Background
Preferentially catalyzes the conversion of 11-deoxycorticosterone to aldosterone via corticosterone and 18-hydroxycorticosterone.
Synonyms
Cytochrome P450 11B2, mitochondrial|Aldosterone synthase (ALDOS) |Aldosterone-synthesizing enzyme|CYPXIB2|Corticosterone 18-monooxygenase, CYP11B2|Cytochrome P-450Aldo|Cytochrome P-450C18|Steroid 11-beta-hydroxylase, CYP11B2|Steroid 18-hydroxylase|CYP11B2
Gene ID
1585
UniProt
P19099
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Cytochrome P450, family 11, subfamily B, polypeptide 2
Target
CYP11B2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IF
Immunogen Sequence
25-183aa

UniProtKB · P19099

Cytochrome P450 11B2, mitochondrial

C11B2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P19099
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CYP11B2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B0ZBE4, Q16726
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Disease variant

Ligand

HemeIronMetal-binding

Biological process

Lipid metabolismSteroid metabolismSteroidogenesis

Cellular component

MembraneMitochondrionMitochondrion inner membrane

Molecular function

MonooxygenaseOxidoreductase

Domain

Transit peptide

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