CXXC5 antibody

CAT: 0710-FNab02113Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab02113Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity) . Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) (PubMed:23303788) . May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788) .

Synonyms

CXXC-type zinc finger protein 5 (CF5) |Putative MAPK-activating protein PM08|Putative NF-kappa-B-activating protein 102|Retinoid-inducible nuclear factor (RINF) |CXXC5

Gene ID

51523

UniProt

Q7LFL8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

CXXC finger 5

Target

CXXC5

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

35-40 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

UniProtKB · Q7LFL8

CXXC-type zinc finger protein 5

CXXC5_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q7LFL8
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CXXC5
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: CF5
EC number: —
Processing: —
Secondary accessions: B3KND0, C8CBA8, Q8TB79, Q9NV51, Q9P0S8

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

DNA-bindingRepressor

Ligand

Metal-bindingZinc

PTM

Phosphoprotein

Biological process

Transcription

Domain

Zinc-finger

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Alternative Products

Catalog	Name
MBS7125367-01	CXXC5 Antibody