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CRHR2 antibody

CAT: 0710-FNab01975Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01975Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Synonyms
Corticotropin-releasing factor receptor 2 (CRF-R-2, CRF-R2, CRFR-2) |Corticotropin-releasing hormone receptor 2 (CRH-R-2, CRH-R2) |CRHR2|CRF2R|CRH2R
Gene ID
1395
UniProt
Q13324
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Corticotropin releasing hormone receptor 2
Target
CRHR2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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