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COPZ1 antibody

CAT: 0710-FNab01875Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01875Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity) . The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
Synonyms
Coatomer subunit zeta-1|Zeta-1-coat protein (Zeta-1 COP) |COPZ1|COPZ
Gene ID
22818
UniProt
P61923
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Coatomer protein complex, subunit zeta 1
Target
COPZ1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
20 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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