COPE antibody

CAT: 0710-FNab01865Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab01865Size:100 µg
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Background
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity) .
Synonyms
Coatomer subunit epsilon|Epsilon-coat protein (Epsilon-COP) |COPE
Gene ID
11316
UniProt
O14579
Host
Rabbit
Reactivity
Human
Immunogen
Coatomer protein complex, subunit epsilon
Target
COPE
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC

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