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COMMD5 antibody

CAT: 0710-FNab01851Size: 100 µgDry Ice: NoHazardous: No
CAT#: FNab01851Size: 100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237) . Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity) . Down-regulates activation of NF-kappa-B (PubMed:15799966) .
Synonyms
COMM domain-containing protein 5|Hypertension-related calcium-regulated gene protein (HCaRG) |COMMD5
Gene ID
54951
UniProt
Q9GZQ3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
COMM domain containing 5
Target
COMMD5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Signal Transduction, Metabolism, Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
25-28 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

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