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CNOT2 antibody

CAT: 0710-FNab01807Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01807Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.
Synonyms
CCR4-NOT transcription complex subunit 2|CCR4-associated factor 2|CNOT2|CDC36|NOT2
Gene ID
4848
UniProt
Q9NZN8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
CCR4-NOT transcription complex, subunit 2
Target
CNOT2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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