CNOT2 antibody
CAT:
710-FNab01807
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CNOT2 antibody
- Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem(ES) cell identity.
- Synonyms: CCR4-NOT transcription complex subunit 2|CCR4-associated factor 2|CNOT2|CDC36|NOT2
- CAS Number: 9007-83-4
- Gene ID: 4848
- UniProt: Q9NZN8
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Immunogen: CCR4-NOT transcription complex, subunit 2
- Target: CNOT2
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, WB
- Field of Research: Epigenetics, Metabolism
- Purification: Immunogen affinity purified
- Dilution: WB: 1:500-1:2000
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 60 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)