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CLU antibody

CAT: 0710-FNab01782Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01782Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Clusterin (Apolipoprotein J) is a 75-80 kDa heterodimeric glycoprotein produced by a wide array of tissues and found in most biologic fluids (PMID: 7648419; 11906815) . It is encoded by one single gene and cleaved posttranslationally into α (34-36 kDa) and β (36-39 kDa) subunits prior to secretion from the cell. Many functions have been described for clusterin, including regulating apoptosis, transporting lipids, controlling cell interactions, regulating complement (PMID: 10694874) .
Synonyms
Clusterin|Aging-associated gene 4 protein|Apolipoprotein J (Apo-J) |Complement cytolysis inhibitor (CLI) |Complement-associated protein SP-40,40|Ku70-binding protein 1|NA1/NA2|Sulfated glycoprotein 2 (SGP-2) |Testosterone-repressed prostate message 2 (TRPM-2) |Clusterin beta chain Alternative names: ApoJalpha|Complement cytolysis inhibitor a chain|SP-40,40 beta-chain|Clusterin alpha chain Alternative names: ApoJbeta|Complement cytolysis inhibitor b chain|SP-40,40 alpha-chain|CLU|APOJ|CLI|KUB1
Gene ID
1191
UniProt
P10909
Host
Mouse
Reactivity
Human
Immunogen
Clusterin
Target
CLU
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Cancer, Immunology, Cardiovascular
Purification
Protein A+G purification
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
5A5
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
100-449aa