CLCA2 antibody

• Background:

  Plays a role in modulating chloride current across the plasma membrane in a calcium-dependent manner, and cell adhesion. Involved in basal cell adhesion and/or stratification of squamous epithelia. May act as a tumor suppressor in breast and colorectal cancer. Plays a key role for cell adhesion in the beginning stages of lung metastasis via the binding to ITGB4.

• Synonyms:

  Calcium-activated chloride channel regulator 2|Calcium-activated chloride channel family member 2 (hCLCA2) |Calcium-activated chloride channel protein 3 (CaCC-3, hCaCC-3) |Calcium-activated chloride channel regulator 2, 109 kDa form|Calcium-activated chloride channel regulator 2, 35 kDa form|CLCA2|CACC3

• Gene ID:

  9635

• UniProt:

  Q9UQC9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Chloride channel accessory 2

• Target:

  CLCA2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  141 kDa, 35-40 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC

• Immunogen Sequence:

  645-901aa