CHST1 antibody

CAT: 0710-FNab01689Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab01689Size:100 µg
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Background
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate(PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose(Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells(HEVs) and play a central role in lymphocyte homing at sites of inflammation.
CAS Number
9007-83-4
Synonyms
Carbohydrate sulfotransferase 1|Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1 (GST-1)|Keratan sulfate Gal-6 sulfotransferase (KS6ST, KSGal6ST, KSST)|CHST1
Gene ID
8534
UniProt
O43916
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
carbohydrate(keratan sulfate Gal-6) sulfotransferase 1
Target
CHST1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
48-55 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

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