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CHRNA10 antibody

CAT: 0710-FNab01675Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01675Size:100 µg
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Background
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
Synonyms
Neuronal acetylcholine receptor subunit alpha-10|Nicotinic acetylcholine receptor subunit alpha-10 (NACHR alpha-10) |CHRNA10|NACHRA10
Gene ID
57053
UniProt
Q9GZZ6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Cholinergic receptor, nicotinic, alpha 10
Target
CHRNA10
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-52 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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