CHL1 antibody

CHL1 antibody

• Background: Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane(By similarity).
• Synonyms: Neural cell adhesion molecule L1-like protein|Close homolog of L1|Processed neural cell adhesion molecule L1-like protein|CHL1|CALL
• CAS Number: 9007-83-4
• Gene ID: 10752
• UniProt: O00533
• Host: Rabbit
• Reactivity: Human, Mouse
• Immunogen: cell adhesion molecule with homology to L1CAM(close homolog of L1)
• Target: CHL1
• Clonality: Polyclonal
• Isotype: IgG
• Applications: ELISA, WB
• Field of Research: Neuroscience, Immunology, Signal Transduction, Developmental biology
• Purification: Immunogen affinity purified
• Dilution: WB: 1:500-1:2000
• Purity: ≥95% as determined by SDS-PAGE
• Form: Liquid
• Molecular Weight: 135 kDa
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)