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CHL1 antibody

CAT: 0710-FNab01655Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01655Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane (By similarity) .
Synonyms
Neural cell adhesion molecule L1-like protein|Close homolog of L1|Processed neural cell adhesion molecule L1-like protein|CHL1|CALL
Gene ID
10752
UniProt
O00533
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Cell adhesion molecule with homology to L1CAM (close homolog of L1)
Target
CHL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Immunology, Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
135 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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