CFTR antibody

• Background:

  Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.

• Synonyms:

  Cystic fibrosis transmembrane conductance regulator (CFTR) |ATP-binding cassette sub-family C member 7|Channel conductance-controlling ATPase|cAMP-dependent chloride channel|CFTR|ABCC7

• Gene ID:

  1080

• UniProt:

  P13569

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)

• Target:

  CFTR

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC, IF

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  IF: 1:50-1:500; IHC: 1:50-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC, IF