CES1 antibody

• Background:

  This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

• Synonyms:

  Liver carboxylesterase 1|Acyl-coenzyme A:cholesterol acyltransferase (ACAT) |Brain carboxylesterase hBr1|Carboxylesterase 1 (CE-1, hCE-1) |Cholesteryl ester hydrolase (CEH) |Cocaine carboxylesterase|Egasyn|HMSE|Methylumbelliferyl-acetate deacetylase 1|Monocyte/macrophage serine esterase|Retinyl ester hydrolase (REH) |Serine esterase 1|Triacylglycerol hydrolase (TGH) |CES1|CES2|SES1

• Gene ID:

  1066

• UniProt:

  P23141

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Carboxylesterase 1 (monocyte/macrophage serine esterase 1)

• Target:

  CES1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Cardiovascular, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  62 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC