CD46 antibody

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CD46 antibody

CAT:

710-FNab01485

Size:

100 µg

Price:

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For price, please contact [email protected].

Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. (Microbial infection) A number of viral and bacterial pathogens seem to bind MCP in order to exploit its immune regulation property and directly induce an immunosuppressive phenotype in T-cells. Acts as a receptor for adenovirus subgroup B2 and Ad3, cultured measles virus and herpesvirus 6(PubMed:10972291, PubMed:12663806, PubMed:12724329, PubMed:12915534, PubMed:14566335, PubMed:15047806, PubMed:15078926, PubMed:15919905, PubMed:16254377). May act as a receptor for pathogenic bacteria Neisseria and Streptococcus pyogenes(PubMed:7708671, PubMed:9379894, PubMed:11260136, PubMed:11971006).
Synonyms: Membrane cofactor protein|TLX|Trophoblast leukocyte common antigen|CD46|MCP|MIC10
Gene ID: 4179
UniProt: P15529
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: CD46 molecule, complement regulatory protein
Target: CD46
Clonality: Polyclonal
Isotype: IgG
Applications: ELISA, WB, IP
Field of Research: Immunology, Metabolism
Purification: Immunogen affinity purified
Dilution: WB: 1:500-1:1000; IP: 1:200-1:1000
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular Weight: 50-56 kDa
Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Complementary Product Range

Our range of products, including CD46 antibody, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

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Cat	Name
FNab01485	CD46 antibody
P4786-03	Recombinant Human CD46
P4786-02	Recombinant Human CD46
P4786-01	Recombinant Human CD46
Pr22517-02	Recombinant Human CD46
Pr22517-04	Recombinant Human CD46
Pr22517-03	Recombinant Human CD46
Pr22517-01	Recombinant Human CD46
EB0180	Bovine CD46 (Membrane cofactor protein) ELISA Kit
EH1452	Human MCP/CD46 (Membrane Cofactor Protein) ELISA Kit