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ENTPD1 antibody

CAT: 0710-FNab01474Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01474Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ENTPD1 (Ectonucleoside triphosphate diphosphohydrolase 1) is also named as CD39, NTPDase 1, Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.It is a noncovalent tetrameric protein and that detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers (PMID: 9733785) .And it is a 70-to 100-kDa protein that is heavily N-glycosylated (PMID:7930580) . It has 3 isoforms produced by alternative splicing. CD39 preferentially occurred as a dimer that could be dissociated into monomeric forms. (PMID: 12694193) . The soluble isoform of CD39 (38-478 amino acid) locates to the extracellular part and FNab01474 recognizes both the 3 isoforms and soluble form of CD39 (38-478aa) molecule.
Synonyms
Ectonucleoside triphosphate diphosphohydrolase 1|ATP diphosphohydrolase (ATP-DPH, ATPDase) |Ecto-ATP diphosphohydrolase 1 (Ecto-ATPDase 1, Ecto-ATPase 1) |Ecto-apyrase|Lymphoid cell activation antigen|Nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) |ENTPD1|CD39
UniProt
P49961
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ectonucleoside triphosphate diphosphohydrolase 1
Target
ENTPD1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, FC, IP
Field of Research
Stem Cells, Immunology, Metabolism, Cancer
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
75-95 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, FC, IP

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