CD320 antibody

CAT: 0710-FNab01466Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab01466Size:100 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD320, also known as 8D6, 8D6A or TCblR, is a single-pass type I membrane protein containing 2 LDL-receptor class A domains. Expressed abundantly on follicular dendritic cells (FDCs), CD320 has been shown to enhance proliferation of germinal center (GC) B cells. It is the receptor for cellular uptake of transcobalamin-bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) . CD320 has a calculated molecular mass of 29 kDa. This antibody detects bands at 50-55 kDa and 60-70 kDa, probably caused by extensive complex glycosylation.
Synonyms
CD320 antigen|8D6 antigen|FDC-signaling molecule 8D6 (FDC-SM-8D6) |Transcobalamin receptor (TCblR) |CD320|8D6A
Gene ID
51293
UniProt
Q9NPF0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
CD320 molecule
Target
CD320
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-55 kDa, 60-70 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
80-282aa

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