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PECAM1 antibody

CAT: 0710-FNab01463Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01463Size:100 µg
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Background
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
Synonyms
Platelet endothelial cell adhesion molecule (PECAM-1) |EndoCAM|GPIIA'|PECA1|PECAM1|CD31
Gene ID
5175
UniProt
P16284
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Platelet/endothelial cell adhesion molecule
Target
PECAM1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Cardiovascular, Immunology, Cancer, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
130 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
28-150aa

UniProtKB · P16284

Platelet endothelial cell adhesion molecule

PECA1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P16284
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PECAM1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PECAM-1
EC number
—
Processing
Precursor
Secondary accessions
A0A075B738, A8K3S7, D3DU31, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesionPhagocytosis

Cellular component

Cell junctionCell membraneMembrane

PTM

Disulfide bondGlycoproteinLipoproteinPalmitatePhosphoprotein

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

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