CD3E antibody

CAT: 0710-FNab01459Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab01459Size:100 µg
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Background
CD3 is a complex of proteins that directly associates with the T cell receptor (TCR) . The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule.
Synonyms
T-cell surface glycoprotein CD3 epsilon chain|T-cell surface antigen T3/Leu-4 epsilon chain|CD3E|T3E
Gene ID
916
UniProt
P07766
Host
Mouse
Reactivity
Human
Immunogen
CD3e molecule, epsilon (CD3-TCR complex)
Target
CD3E
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC, IF, FC
Field of Research
Cancer, Immunology, Signal Transduction
Purification
Protein A+G purification
Dilution
WB: 1:2000 - 1:20000; IHC: 1:1000 - 1:10000; IF: 1:50 - 500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
23 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2E4
Tested Applications
ELISA, WB, IHC, IF, FC
Immunogen Sequence
1-207aa

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