RegisterLogin

CD22 antibody

CAT: 0710-FNab01444Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab01444Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Synonyms
B-cell receptor CD22|B-lymphocyte cell adhesion molecule (BL-CAM) |Sialic acid-binding Ig-like lectin 2 (Siglec-2) |T-cell surface antigen Leu-14|CD22|SIGLEC2
Gene ID
933
UniProt
P20273
Host
Mouse
Reactivity
Human
Immunogen
CD22 molecule
Target
CD22
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Stem Cells, Immunology, Signal Transduction, Cancer
Purification
Protein A+G purification
Dilution
WB : 1:1000-1:10000; IHC : 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
135 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
7D10
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
340-687aa

Related Products

CatalogName
APC-30034-01APC Anti-Human CD22 (HIB22)
PE-30034-01PE Anti-Human CD22 (HIB22)
FITC-30034-01FITC Anti-Human CD22 (HIB22)
P1813Recombinant human B-cell receptor CD22
FITC-30016-01FITC Anti-Mouse CD22 (Cy34.1)
APC-30016-01APC Anti-Mouse CD22 (Cy34.1)
PC7-30016-01PE-Cy7 Anti-Mouse CD22 (Cy34.1)
PC5-30016-01PE-Cy5 Anti-Mouse CD22 (Cy34.1)
PC55-30016-01PE-Cy5.5 Anti-Mouse CD22 (Cy34.1)
FNab01447CD23 antibody

Alternative Products

CatalogName
MBS8517032-01CD22 Antibody

Popular Products