Products for Research Use Only
RegisterLogin

MCAM antibody

CAT: 0710-FNab01429Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab01429Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CD146, also known as melanoma cell adhesion molecule (MCAM) or MUC18, originally identified as a biomarker of melanoma progression, is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily (PMID: 8378324) . Structurally, it consists of five Ig domains, a transmembrane domain, and a cytoplasmic region. In normal adult tissue, CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis, and has been used as marker of circulating endothelium cells (CECs) (PMID: 19356677) .
Synonyms
Cell surface glycoprotein MUC18|Cell surface glycoprotein P1H12|Melanoma cell adhesion molecule|Melanoma-associated antigen A32|Melanoma-associated antigen MUC18|S-endo 1 endothelial-associated antigen|MCAM|MUC18|CD146
Gene ID
4162
UniProt
P43121
Host
Mouse
Reactivity
Human
Immunogen
Melanoma cell adhesion molecule
Target
MCAM
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC, FC
Field of Research
Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
Purification
Protein A+G purification
Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
113-120 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
0E4
Tested Applications
ELISA, WB, IHC, FC
Immunogen Sequence
26-350aa

Related Products

CatalogName
EH1880Human MCAM (Cell surface glycoprotein MUC18) ELISA Kit
EH0880Human MCAb (Melanocyte antibody) ELISA Kit
EH14848Human MCAT (Malonyl-CoA-acyl carrier protein transacylase, mitochondrial) ELISA Kit
FNab11062CA125 antibody (capture antibody)
FNab11060AFP antibody (capture antibody)
FNab11045-01CEA antibody (detection antibody)
FNab11061CA125 antibody (detection antibody)
FNab11059AFP antibody (detection antibody)
FNab11046-01CEA antibody (capture antibody)
FNab09471WAS antibody

Alternative Products

CatalogName
GWB-MW882IMCAM Antibody

Popular Products