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ANPEP antibody

CAT: 0710-FNab01417Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01417Size:100 µg
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Background
CD13 is also named as APN, ANPEP (aminopeptidase N), PEPN and belongs to the peptidase M1 family. It is a 150-kD cell surface glycoprotein originally identified on subsets of normal and malignant human myeloid cells.CD13 is an important regulator of angiogenesis where its expression on activated blood vessels is induced by angiogenic signals.
Synonyms
Aminopeptidase N (AP-N, hAPN) |Alanyl aminopeptidase|Aminopeptidase M (AP-M) |Microsomal aminopeptidase|Myeloid plasma membrane glycoprotein CD13|gp150|ANPEP|APN|CD13|PEPN
Gene ID
290
UniProt
P15144
Host
Mouse
Reactivity
Human
Immunogen
Alanyl (membrane) aminopeptidase
Target
ANPEP
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:10000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
150 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
6H5
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
610-967aa

UniProtKB · P15144

Aminopeptidase N

AMPN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15144
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ANPEP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
AP-N, hAPN
EC number
3.4.11.2
Processing
—
Secondary accessions
Q16728, Q6GT90, Q8IUK3, Q8IVH3, Q9UCE0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

AminopeptidaseDevelopmental proteinHost cell receptor for virus entryHydrolaseMetalloproteaseProteaseReceptor

Biological process

AngiogenesisDifferentiationHost-virus interaction

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinSulfation

Ligand

Metal-bindingZinc

Domain

Signal-anchorTransmembraneTransmembrane helix

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