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CARD11 antibody

CAT: 0710-FNab01268Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01268Size:100 µg
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Background
Involved in the costimulatory signal essential for T-cell receptor (TCR) -mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
Synonyms
Caspase recruitment domain-containing protein 11|CARD-containing MAGUK protein 1 (Carma 1) |CARD11|CARMA1
Gene ID
84433
UniProt
Q9BXL7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Caspase recruitment domain family, member 11
Target
CARD11
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC
Field of Research
Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
133 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC

UniProtKB · Q9BXL7

Caspase recruitment domain-containing protein 11

CAR11_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BXL7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CARD11
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A4D1Z7, Q2NKN7, Q548H3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Domain

Coiled coil

Cellular component

CytoplasmMembrane

Disease

Disease variant

PTM

Disulfide bondIsopeptide bondPhosphoprotein

Biological process

Immunity

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