CAMKK2 antibody
CAT:
710-FNab01238
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CAMKK2 antibody
- Background: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase(AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals(By similarity). Seems to be involved in hippocampal activation of CREB1(By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
- Synonyms: Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2, CaM-kinase kinase 2, CaMKK 2)|Calcium/calmodulin-dependent protein kinase kinase beta (CaM-KK beta, CaM-kinase kinase beta, CaMKK beta)|CAMKK2|CAMKKB|KIAA0787
- CAS Number: 9007-83-4
- Gene ID: 10645
- UniProt: Q96RR4
- Host: Rabbit
- Reactivity: Human, Mouse
- Immunogen: calcium/calmodulin-dependent protein kinase kinase 2, beta
- Target: CAMKK2
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, WB, IF, IHC
- Field of Research: Neuroscience, Signal Transduction, Metabolism
- Purification: Immunogen affinity purified
- Dilution: WB: 1:500-1:2000; IF: 1:20-1:200; IHC: 1:20-1:200
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 55-60 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)