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C4 (alpha chain) antibody

CAT: 0710-FNab01111Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01111Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Complement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular wights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody can recognize C4 precursor, C4 alpha chain, C4b, and C4d.
Synonyms
Complement C4-A|Acidic complement C4|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2|Complement C4 beta chain|Complement C4-A alpha chain|C4a anaphylatoxin|C4b-A|C4d-A|Complement C4 gamma chain|C4A|CO4|CPAMD2
Gene ID
720
UniProt
P0C0L4
Host
Rabbit
Reactivity
Human
Immunogen
Complement component 4A (Rodgers blood group)
Target
C4 (alpha chain)
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:6000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
95 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
1028-1336