BCL2 antibody

CAT: 0710-FNab00840Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab00840Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) . May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785) .
Synonyms
Apoptosis regulator Bcl-2|BCL2
Gene ID
596
UniProt
P10415
Host
Mouse
Reactivity
Human
Immunogen
B-cell CLL/lymphoma 2
Target
BCL2
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IP, IHC
Field of Research
Neuroscience, Cancer, Immunology, Cardiovascular
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:10000; IP: 1:500-1:5000; IHC: 1:100-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
26 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
8A10
Tested Applications
ELISA, WB, IP, IHC
Immunogen Sequence
1-239aa

Related Products

CatalogName
P2028-01Recombinant Human BCL2
P4667-01Recombinant Mouse Bcl2
EM0454Mouse Bcl2 (Apoptosis regulator Bcl-2) ELISA Kit
EH2690Human BAK1 (Bcl2 Antagonist/Killer 1) ELISA Kit
EH1736Human BAD (Bcl2 antagonist of cell death) ELISA Kit
EH2698Human BCL2L1/BCL-X (Bcl-2 Like Protein 1/Bcl2 Associated X Protein) ELISA Kit
EH2689Human BAG3 (Bcl2 Associated Athanogene 3) ELISA Kit
ER0760Rat BAK1 (BCL2 Antagonist/Killer 1) ELISA Kit
EH4053Human BNIP3 (BCL2/adenovirus E1B 19 kDa protein-interacting protein 3) ELISA Kit
EM6245Mouse BNIP3 (BCL2/adenovirus E1B 19 kDa protein-interacting protein 3) ELISA Kit

Alternative Products

CatalogName
MBS8503534-01Bcl2 Antibody

Popular Products