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BAX antibody

CAT: 0710-FNab00811Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00811Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Synonyms
Apoptosis regulator BAX|Bcl-2-like protein 4 (Bcl2-L-4) |BAX|BCL2L4
Gene ID
581
UniProt
Q07812
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
BCL2-associated X protein
Target
BAX
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB,IHC,IF
Field of Research
Neuroscience, Cancer, Developmental biology
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:10000; IHC: 1:400-1:1000; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
21 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
5F4
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
1-192aa

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