BATF2 antibody

CAT: 0710-FNab00808Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab00808Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8 (+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity) . Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
Synonyms
Basic leucine zipper transcriptional factor ATF-like 2 (B-ATF-2) |Suppressor of AP-1 regulated by IFN (SARI) |BATF2
Gene ID
116071
UniProt
Q8N1L9
Host
Rabbit
Reactivity
Human
Immunogen
Basic leucine zipper transcription factor, ATF-like 2
Target
BATF2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISAA, WB, IP
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000; IP: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
29 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISAA, WB, IP

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