BAK1 antibody

• Background :

  The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

• Synonyms :

  Bcl-2 homologous antagonist/killer|Apoptosis regulator BAK|Bcl-2-like protein 7 (Bcl2-L-7) |BAK1|BAK|BCL2L7|CDN1

• Gene ID :

  578

• UniProt :

  Q16611

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  BCL2-antagonist/killer 1

• Target :

  BAK1

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Neuroscience, Cancer, Immunology, Cardiovascular

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  26 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC