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BAK1 antibody

CAT: 0710-FNab00796Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00796Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Synonyms
Bcl-2 homologous antagonist/killer|Apoptosis regulator BAK|Bcl-2-like protein 7 (Bcl2-L-7) |BAK1|BAK|BCL2L7|CDN1
Gene ID
578
UniProt
Q16611
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
BCL2-antagonist/killer 1
Target
BAK1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Cancer, Immunology, Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
26 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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