AURKB antibody

CAT: 0710-FNab00747Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab00747Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Aurora B (AURKB) is also named as aurora kinase B, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5 and belongs to the Aurora subfamily. Aurora kinase B is a chromosomal passenger serine/threonine protein kinase that regulates accurate chromosomal segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachments, and regulation of the mitotic checkpoint (PMID:18311747) . Expression levels of AURKB are increased in the anaplastic thyroid carcinoma cell lines ARO, Cal 62, and KAT-4 (PMID:15562011) .
Synonyms
Aurora kinase B|Aurora 1|Aurora- and IPL1-like midbody-associated protein 1 (AIM-1) |Aurora/IPL1-related kinase 2 (ARK-2, Aurora-related kinase 2) |STK-1|Serine/threonine-protein kinase 12|Serine/threonine-protein kinase 5|Serine/threonine-protein kinase aurora-B|AURKB|AIK2|AIM1|AIRK2|ARK2|STK1|STK12|STK5
Gene ID
9212
UniProt
Q96GD4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Aurora kinase B
Target
AURKB
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cancer, Cell Division and Proliferation, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
16 kDa, 35-45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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