AURKB antibody

• Background:

  Aurora B (AURKB) is also named as aurora kinase B, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5 and belongs to the Aurora subfamily. Aurora kinase B is a chromosomal passenger serine/threonine protein kinase that regulates accurate chromosomal segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachments, and regulation of the mitotic checkpoint (PMID:18311747) . Expression levels of AURKB are increased in the anaplastic thyroid carcinoma cell lines ARO, Cal 62, and KAT-4 (PMID:15562011) .

• Synonyms:

  Aurora kinase B|Aurora 1|Aurora- and IPL1-like midbody-associated protein 1 (AIM-1) |Aurora/IPL1-related kinase 2 (ARK-2, Aurora-related kinase 2) |STK-1|Serine/threonine-protein kinase 12|Serine/threonine-protein kinase 5|Serine/threonine-protein kinase aurora-B|AURKB|AIK2|AIM1|AIRK2|ARK2|STK1|STK12|STK5

• Gene ID:

  9212

• UniProt:

  Q96GD4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Aurora kinase B

• Target:

  AURKB

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Cancer, Cell Division and Proliferation, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:2000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  16 kDa, 35-45 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC