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ASTL antibody

CAT: 0710-FNab00651Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00651Size:100 µg
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Background
Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity) .
Synonyms
Astacin-like metalloendopeptidase|Oocyte astacin|Ovastacin|ZP2-proteinase|ASTL
Gene ID
431705
UniProt
Q6HA08
Host
Rabbit
Reactivity
Human
Immunogen
Astacin-like metallo-endopeptidase (M12 family)
Target
ASTL
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Stem Cells, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
46 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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