ASTL antibody

• Background:

  Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity) .

• Synonyms:

  Astacin-like metalloendopeptidase|Oocyte astacin|Ovastacin|ZP2-proteinase|ASTL

• Gene ID:

  431705

• UniProt:

  Q6HA08

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Astacin-like metallo-endopeptidase (M12 family)

• Target:

  ASTL

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Stem Cells, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:1000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  46 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB