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ARL2 antibody

CAT: 0710-FNab00574Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00574Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP) . GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca (2+) -dependent release of acetylcholine. Required for normal progress through the cell cycle.
Synonyms
ADP-ribosylation factor-like protein 2|ARL2
Gene ID
402
UniProt
P36404
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ADP-ribosylation factor-like 2
Target
ARL2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
21-25 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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