ARFGAP1 antibody

• Background:

  The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.

• Synonyms:

  ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) |ADP-ribosylation factor 1 GTPase-activating protein (ARF1 GAP) |ARF1-directed GTPase-activating protein|ARFGAP1|ARF1GAP

• Gene ID:

  55738

• UniProt:

  Q8N6T3

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  ADP-ribosylation factor GTPase activating protein 1

• Target:

  ARFGAP1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  45 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF