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APLP1 antibody

CAT: 0710-FNab00486Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00486Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms
Amyloid beta precursor like protein 1|Amyloid beta (A4) precursor-like protein 1|Amyloid-like protein 1 (APLP, APLP-1) |C30|APLP1
Gene ID
333
UniProt
P51693
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amyloid beta (A4) precursor-like protein 1
Target
APLP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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