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APLF antibody

CAT: 0710-FNab00484Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00484Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly (ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
Synonyms
Aprataxin and PNK-like factor|Apurinic-apyrimidinic endonuclease APLF|PNK and APTX-like FHA domain-containing protein|XRCC1-interacting protein 1|APLF|C2orf13|PALF|XIP1
Gene ID
200558
UniProt
Q8IW19
Host
Rabbit
Reactivity
Human
Immunogen
Aprataxin and PNKP like factor
Target
APLF
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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