API5 antibody

• Background :

  Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

• Synonyms :

  Apoptosis inhibitor 5 (API-5) |Antiapoptosis clone 11 protein (AAC-11) |Cell migration-inducing gene 8 protein|Fibroblast growth factor 2-interacting factor (FIF) |Protein XAGL|API5

• Gene ID :

  8539

• UniProt :

  Q9BZZ5

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Apoptosis inhibitor 5

• Target :

  API5

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF

• Field of Research :

  Neuroscience

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50 - 1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  50-55 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF