API5 antibody

• Background:

  Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

• Synonyms:

  Apoptosis inhibitor 5 (API-5) |Antiapoptosis clone 11 protein (AAC-11) |Cell migration-inducing gene 8 protein|Fibroblast growth factor 2-interacting factor (FIF) |Protein XAGL|API5

• Gene ID:

  8539

• UniProt:

  Q9BZZ5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Apoptosis inhibitor 5

• Target:

  API5

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Neuroscience

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  50-55 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF