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API5 antibody

CAT: 0710-FNab00482Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab00482Size:100 µg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Synonyms
Apoptosis inhibitor 5 (API-5) |Antiapoptosis clone 11 protein (AAC-11) |Cell migration-inducing gene 8 protein|Fibroblast growth factor 2-interacting factor (FIF) |Protein XAGL|API5
Gene ID
8539
UniProt
Q9BZZ5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Apoptosis inhibitor 5
Target
API5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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