APH1A antibody

• Background :

  Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein) . It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.

• Synonyms :

  Gamma-secretase subunit APH-1A (APH-1a) |Aph-1alpha|Presenilin-stabilization factor|APH1A|PSF

• Gene ID :

  51107

• UniProt :

  Q96BI3

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Anterior pharynx defective 1 homolog A

• Target :

  APH1A

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB

• Field of Research :

  Neuroscience, Immunology, Cardiovascular, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:1000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  30 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB

• Immunogen Sequence :

  230-265