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APH1A antibody

CAT: 0710-FNab00481Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00481Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein) . It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
Synonyms
Gamma-secretase subunit APH-1A (APH-1a) |Aph-1alpha|Presenilin-stabilization factor|APH1A|PSF
Gene ID
51107
UniProt
Q96BI3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Anterior pharynx defective 1 homolog A
Target
APH1A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Immunology, Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
30 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
230-265

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