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ANGPTL3 antibody

CAT: 0710-FNab00398Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00398Size:100 µg
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Background
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
Synonyms
Angiopoietin-related protein 3|Angiopoietin-5 (ANG-5) |Angiopoietin-like protein 3|ANGPTL3 (17-221) |ANGPTL3 (17-224) |ANGPTL3|ANGPT5
Gene ID
27329
UniProt
Q9Y5C1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Angiopoietin-like 3
Target
ANGPTL3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
53 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
17-120AA

UniProtKB · Q9Y5C1

Angiopoietin-related protein 3

ANGL3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y5C1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ANGPTL3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A0JLS0, B1ALJ0, B2RCW1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

AngiogenesisCell adhesionLipid metabolism

Cellular component

Cell projectionSecreted

Domain

Coiled coilSignal

PTM

Disulfide bondGlycoprotein

Molecular function

Heparin-binding

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