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GLA antibody

CAT: 0710-FNab00330Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00330Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GLA, also named as Melibiase, Agalsidase and Alpha-galactosidase A, belongs to the glycosyl hydrolase 27 family. It hydrolyzes terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids. Fabry disease is an X-linked lysosomal storage disorder resulting from the deficient activity of GLA. Enzyme replacement therapy (ERT) with GLA is currently the most effective therapeutic strategy for patients with Fabry disease, a lysosomal storage disease.
Synonyms
Alpha-galactosidase A|Alpha-D-galactosidase A|Alpha-D-galactoside galactohydrolase|Galactosylgalactosylglucosylceramidase GLA|Melibiase|GLA
Gene ID
2717
UniProt
P06280
Host
Mouse
Reactivity
Human
Immunogen
Galactosidase, alpha
Target
GLA
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IHC, IF
Field of Research
Cardiovascular, Metabolism, Signal Transduction
Purification
Protein A+G purification
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
49 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
7F1
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
80-429aa

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