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AK2 antibody

CAT: 0710-FNab00244Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00244Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
Synonyms
Adenylate kinase 2, mitochondrial (AK 2) |ATP-AMP transphosphorylase 2|ATP:AMP phosphotransferase|Adenylate monophosphate kinase|Adenylate kinase 2, mitochondrial, N-terminally processed|AK2|ADK2
Gene ID
204
UniProt
P54819
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Adenylate kinase 2
Target
AK2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
33 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
161-239aa