AFF4 antibody

CAT: 0710-FNab00197Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab00197Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.
Synonyms
AF4/FMR2 family member 4|ALL1-fused gene from chromosome 5q31 protein (Protein AF-5q31) |Major CDK9 elongation factor-associated protein|AFF4|AF5Q31|MCEF
Gene ID
27125
UniProt
Q9UHB7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
AF4/FMR2 family, member 4
Target
AFF4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Cancer, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IP: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
150 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

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