ADIPOQ antibody
CAT:
710-FNab00170
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ADIPOQ antibody
- Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
- Synonyms: Adiponectin|30 kDa adipocyte complement-related protein|Adipocyte complement-related 30 kDa protein (ACRP30)|Adipocyte, C1q and collagen domain-containing protein|Adipose most abundant gene transcript 1 protein (apM-1)|Gelatin-binding protein|ADIPOQ|ACDC|ACRP30|APM1|GBP28
- CAS Number: 9007-83-4
- Gene ID: 9370
- UniProt: Q15848
- Host: Mouse
- Reactivity: Human, Mouse
- Immunogen: adiponectin, C1Q and collagen domain containing
- Target: ADIPOQ
- Clonality: Monoclonal
- Isotype: IgG2a
- Clone: 6E1
- Applications: ELISA, WB
- Field of Research: Signal Transduction, Metabolism
- Purification: Protein A+G purification
- Dilution: WB: 1:500-1:2000
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 26 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)