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ADCY1 antibody

CAT: 0710-FNab00155Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00155Size:100 µg
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Background
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels(By similarity). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina(By similarity).
CAS Number
9007-83-4
Synonyms
Adenylate cyclase type 1|ATP pyrophosphate-lyase 1|Adenylate cyclase type I|Adenylyl cyclase 1|Ca(2+)/calmodulin-activated adenylyl cyclase|ADCY1
Gene ID
107
UniProt
Q08828
Host
Rabbit
Reactivity
Human
Immunogen
adenylate cyclase 1(brain)
Target
ADCY1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
123 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

UniProtKB · Q08828

Adenylate cyclase type 1

ADCY1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q08828
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADCY1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
4.6.1.1
Processing
—
Secondary accessions
A4D2L8, Q75MI1
Protein keywords

Ligand

ATP-bindingMagnesiumManganeseMetal-bindingNucleotide-binding

Biological process

Biological rhythmscAMP biosynthesis

Molecular function

Calmodulin-bindingLyase

Cellular component

Cell membraneCytoplasmMembrane

Disease

DeafnessNon-syndromic deafness

PTM

GlycoproteinPhosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatTransmembraneTransmembrane helix

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